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The IC 50 of MP1 was 0.096 μM in BE-2c cells compared to 0.89 μM in IMR, and 50 μM in SKN-AS. The IC 50 of MP1 plus TEM in BE-2c cells was 0.023 μM. MP1 inhibited metabolism leading to quiescence and produced a decline in cell cycle S-phase. Electron microscopy showed cristae loss and rounding up of mitochondria. yonex astrox 99 play

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